Description: Genizer Jacketed Liposome Extruders is compressed air driven, temperature controlled, from testing to manufacture production of liposome and lipopolyplex for drug and gene delivery.
The Jacketed Liposome Extruders are designed to generate homogeneous unilamellar liposomes and Lipopolyplex. Extrusion is a one-step procedure that produces liposomes by forcing lipid suspensions of drug, protein or gene through track-etched filters with defined pore size. It is relatively gentle, exposing the formulation to moderate pressures up to 1,500 psi at controlled temperatures. The Genizer Extruder is easily cleaned and suitable for sterilization, compliance with FDA and GMP sanitary standards in Pharmaceuticals.
Specifications
Catalog No. |
Gextruder-10ml, Gextruder-100ml, Gextruder-800ml, Gextruder-3000ml, Gextruder-10000ml, Gextruder-Customize |
Description |
Jacketed Temperature-control Liposome Extruder |
Min. Sample Size |
5ml, 20ml, 200ml, 500ml, 10,000ml, TBD |
Temperature Limit |
80ºC (176ºF) |
Power Requirements |
Compressed Gas |
Feed Reservoir |
10ml, 100ml, 800ml, 3000ml, 10,000ml, TBD |
Cleaning |
Flush to clean |
Sterilizing |
Whole unit autoclavable |
Max. Pressure |
3,000psi |
Application |
Liposome formulation up to production scale |
Standard Features
Inlet type |
3/8" High pressure coupling |
Outlet type |
3/8" High pressure coupling |
Feed Reservoir |
Temperature control jacketed cylinder |
Nitrogen Line |
G5/8" - 14 TPI BSP inlet Nitrogen High pressure soft tubing |
Nano membrane |
100nm track-etched polycarbonate membrane |
Compatibility |
Some Parts are compatible with Lipex™ in Northern Lipids |
Product material |
316L stainless steel, Viton |
Material standard |
Compliance with FDA and GMP sanitary standards |
Warranty |
1 year against any manufacturing defects |
Option Features
Detector |
Pressure gauge, Pressure transducer, Temperature transducer |
Inlet type |
Tri-clamp or Luer |
Outlet type |
Tri-clamp or Luer |
Multi Extruder |
Parallel or Series connection of Multi Extruder |
Nano membrane |
30, 50, 80, 200, 400, 800nm track-etched membrane |
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